Adipose tissue arachidonic acid and the metabolic syndrome in Costa Rican adults

Año de publicación

2007

UUID

c5f664aa-86f2-494f-8744-5d933cf904fb

Resumen

Arachidonic acid, an n-6 polyunsaturated fatty acid (PUFA), is a major component of mammalian cell membranes and may account for up to 25% of all phospholipid fatty acids. Although it is consumed in the diet in meats, eggs, and some fish, it is also synthesized in the liver from linoleic acid, the most abundant dietary PUFA, and transported to other cell types via serum albumin or lipoproteins. A major function of arachidonic acid is to serve as a precursor to the eicosanoid family of autocrine and paracrine hormones that modulates immune and inflammatory responses in the body. Additionally, there is evidence that arachidonic acid may act as a transcriptional regulator by modulating signal transduction at the cell surface, by altering membrane fluidity, or cell surface interactions by acylating membrane proteins.

Publicador

Clinical Nutrition, no. 26

Enlace del origen de la publicación

Documentación restringida

Sí

Tipo de publicación

Article

Descriptores

• OBESIDAD
• INSULINA
• SINDROME METABOLICO